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Erythema nodosum in association with newly diagnosed hairy cell leukemia and group C streptococcus infection.

Patel RR, Kirkland EB, Nguyen DH, Cooper BW, Baron ED, Gilliam AC

Department of Dermatology, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, OH, USA.

Erythema nodosum is an inflammatory reaction of the skin characterized by tender erythematous patches or nodules, usually located on the lower extremities. This report illustrates an association of erythema nodosum with a rare malignancy and an uncommon infectious agent in humans. There are many diseases associated with erythema nodosum; we propose that hairy cell leukemia and group C streptococcus be considered among this list.

Published 24 March 2008 in Am J Dermatopathol, 30(2): 160-2.
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