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Early sequential development of infective dermatitis, human T cell lymphotropic virus type 1-associated myelopathy, and adult T cell leukemia/lymphoma.

Farre L, de Oliveira Mde F, Primo J, Vandamme AM, Van Weyenbergh J, Bittencourt AL

Laboratory of Immunoregulation and Microbiology, Centro de Pesquisa Conçalo Moniz-Fundação Oswaldo Cruz, Bahia, Brazil. lourdesfarre@hotmail.com

We describe a patient with human T cell lymphotropic virus type 1 (HTLV-1)-associated infective dermatitis who developed HTLV-1-associated myelopathy/tropical spastic paraparesis and adult T cell leukemia/lymphoma at 16 years of age. Long inverse polymerase chain reaction was used to demonstrate monoclonal integration of proviral DNA in the lymphomatous skin lesion.

Published 9 January 2008 in Clin Infect Dis, 46(3): 440-2.
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