Skin Rashes Research Today is a free monthly online journal that collates and summarizes the latest research about Skin Rashes, including details on dermatitis, itches, creams, medication, treatment.

Filaggrin's fuller figure: a glimpse into the genetic architecture of atopic dermatitis.

Sandilands A, Smith FJ, Irvine AD, McLean WH

Epithelial Genetics Group, Human Genetics Unit, University of Dundee, Dundee, UK.

Prevalent mutations in the FLG gene underlie the common skin disorder ichthyosis vulgaris and are significant risk factors for atopic dermatitis (eczema). The recent publication of a strategy to sequence this difficult gene identifies a spectrum of both prevalent and rare mutations that collectively have a significant impact on susceptibility to atopic disease.

Published 15 May 2007 in J Invest Dermatol, 127(6): 1282-4.
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