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Treatment of toxic epidermal necrolysis in a pediatric patient with a nanocrystalline silver dressing.

Asz J, Asz D, Moushey R, Seigel J, Mallory SB, Foglia RP

Division of Pediatric Surgery and Pediatric Acute Wound Service, St Louis Children's Hospital and Washington University School of Medicine, St Louis, MO 63110, USA.

BACKGROUND/PURPOSE: To report a case of toxic epidermal necrolysis (TEN) involving 90% body surface area, successfully treated with a nanocrystalline silver dressing (Acticoat, Smith & Nephew, Largo, FL). METHODS: A review of the hospital and acute wound center patient records and the recent English medical literature regarding TEN and nanocrystalline silver dressing. RESULTS: We found only 1 report of TEN treated with a nanocrystalline silver dressing. The nanocrystalline silver dressing was both effective in preventing wound infection and convenient for treating our patient with TEN. CONCLUSION: The use of nanocrystalline silver dressing should be considered for the treatment of TEN.

Published 12 December 2006 in J Pediatr Surg, 41(12): e9-12.
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