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Erythroderma with lichenoid granulomatous features induced by erythropoietin.

Wolf IH, Smolle J, Cerroni L, Kerl H

Department of Dermatology, University of Graz, Graz, Austria. ingrid.wolf@meduni-graz.at

The increasing use of new drugs in cancer therapy, especially growth factors, hormones, and chemotherapies resulted in several reports of unusual skin eruptions. We studied a patient with erythroderma who had received erythropoietin because of myeloma with tumor anemia. The histological features were characterized by a lichenoid, focally granulomatous infiltrate with predominance of histiocytes. It is important for dermatopathologists to recognize this interesting pattern induced by erythropoietin.

Published 6 April 2005 in J Cutan Pathol, 32(5): 371-4.
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