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Chronic actinic dermatitis associated with adult T-cell leukemia.

Sugita K, Shimauchi T, Tokura Y

Department of Dermatology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan. k-sugita@med.uoeh-u.ac.jp

We describe a patient with chronic actinic dermatitis that occurred with the progress of adult T-cell leukemia. Immunohistochemically, CD8 + T cells, but not CD4 + cells, predominantly infiltrated the lichenoid lesional skin, indicating that the eruption was induced by reactive, normal CD8 + T cells but not adult T-cell leukemia cells. Our patient suggests that chronic actinic dermatitis may occur in association with the advanced human T-lymphotrophic virus-I infectious disorder.

Published 4 February 2005 in J Am Acad Dermatol, 52(2): 38-40.
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